Heather M. Stapleton
Assistant Professor of Environmental Chemistry (primary appt: Nicholas School of the Environment)
Dr. Stapleton's research focuses on understanding the fate and transformation of organic contaminants in aquatic systems and in indoor environments. Her main focus has been on the bioaccumulation and biotransformation of brominated flame retardants, and specifically polybrominated diphenyl ethers,(PBDEs). Her current research projects explore the routes of human exposure to flame retardant chemicals and examine the way these compounds are photodegraded and metabolized using mass spectrometry to identify breakdown products/metabolites. She uses both in vivo techniques iwth fish, and in vitro techniques with cell cultures to examine metabolism of this varied class of chemicals. Also of interest to Dr. Stapleton is the study of the fate of PBDEs in the environment which may lead to bioaccumulation in aquatic systems and examining their bioavailability under different environmental conditions.
- Office Location: A220 LSRC
- Office Phone: (919) 613-8717
- Email Address:
|PhD Environmental Chemistry||University of Maryland||2003|
|MS Environmental Chemistry||University Maryland||2000|
|BS Marine Chemistry||Southampton College||1997|
Awards, Honors, and Distinctions:
- Top Science Paper Published in Environmental Science & Technology, January, 2012
- Editorial Advisory Board Member for Environmental Science & Technology, January, 2011
- Science Communications Fellow, Enviornmental Health Sciences
- Science Communications Fellow, Environmental Health Sciences, December, 2009
- Outstanding New Enviornmental Scientist Award, National Institute of Environmental Health Sciences, July, 2008
- CEE 563.01 - CHEM FATE ORG COMPOUNDS
- ENVIRON 898.07 - PROGRAM AREA SYMPOSIUM
Representative Publications: (More Publications)
- McClain, V, Stapleton, H.M., Tilton F., Gallagher, E.P., BDE 49 and Developmental Toxicity in Zebrafish., Comparative Biochem & Physiol C, vol 155 no. 2 (2012), pp. 253-258.
- Ashley, J.T.F., Vasquez, M.A., Zelanko, P., McKinley, E., Schafer, M., Zaoudeh, L., Horwitz, R., Stapleton, H.M., Velinsky, D.J., Trophic Transfer of Polybrominated Diphenyl Ethers and Polychlorinated Biphenyls in a Tidal Freshwater Marsh., Chemistry & Ecology, vol 28 no. 4 (2012), pp. 305-325.
- Bearr, J.S., Mitchelmore, C.L., Roberts, S.C., Stapleton. H.M., Species specific differences in the in vitro metabolism of the flame retardant mixture, Firemaster® BZ 54., Aquatic Toxicol, vol 124-125 (2012), pp. 41-47.
- Roberts, S.C., Macaulay, L.J., Stapleton, H.M., . In Vitro Metabolism of the Brominated Flame Retardants 2-ethylhexyl-2,3,4,5 tetrabromobenzoate (TBB) and Bis-2-ethylhexyl-2,3,4,5 tetrabromophthalate (TBPH) in Human and Rat Tissues., Chemical Research in Toxicology, vol 25 no. 7 (2012), pp. 1435-1441.
- Klosterhaus, S., Stapleton, H.M., LaGuardia, M.J., Greig, D.J., Brominated and Chlorinated Flame Retardants in San Francisco Bay Sediments and Wildlife., Environment International, vol 47 no. 56-65 (2012).